Daily Health Tip
For 3 Sep 2019
Laboratory Tests for Jaundice ( Infective Hepatitis )
By Prof Dr R R Deshpande ( M- 9226810630 )
Mail ID – firstname.lastname@example.org
If any patient comes with complaints like Severe Anorexia ,Nausea ,Vomiting ,Pain in right upper quadrant of abdomen ,also some times fever with chill .Loss of Appetite or Anorexia is so severe that even patient do not want see at food .--Then Doctor suspects Jaundice
When doctor examines he finds soft & tender Liver .Then doctor checks upper Palpebral Conjunctiva in sun light or day light ( & not in Tube light or Lamp Light ) for Yellow discoloration .This is called as Icterus . some times patient may complain dark yellow or High coloured urine
Then doctor suspects that patient may have Jaundice or Infective Hepatitis due to Virus A ,due to contaminated water .
Then to confirm this provisional diagnosis doctors asks to do Urine Routine Examination .In the report if Bile Salts & Bile Pigments are present ,then patient is suffering from Jaundice
Jaundice is a inflammation of Liver i.e Hepatitis .Next Doctor advice LFT = Liver Function Tests
These tests gives more idea about Type of Jaundice & Severity of Jaundice
Let us see details of LFT & their Normal values & if raised ,what is it’s significance ?
Serum Bilirubin -- Bilirubin is breakdown product of Haemoglobin .Unconjugated or Indirect Bilirubin is converted to Conjugated or Direct Bilirubin in Liver .This is excreted through bile into small intestine .
In Jaundice Blood Bilirubin Level Increases
Total Bilirubin = 0.1 to 1.2 mg %
Direct Bilirubin = up to 0.3 mg %
Indirect Bilirubin = 0.1 to 1 mg%
Indirect Bilirubin increases in Jaundice due to Pre Hepatic Causes like Haemolytic Jaundice
Direct Bilirubin Increases in Infective Hepatitis or Obstructive Jaundice
In Jaundice Liver Enzymes levels are also increased
SGPT = Serum Glutamate Pyruvate Transaminase
This is also called as ALT = Alanine Amino Trasferase
Norma Value = 5 to 35 IU /Lit
In Obstructive Jaundice ,due to Gall stones or Cancer ,Serum Alkaline Phosphatase level becomes very High
Normal value = In Adults = 100 to 250 IU /L
In Children = 250 to 770 IU/L
In obstructive Jaundice patients complains of severe Itching & spasmodic pain in abdomen .Here Jaundice is deep & serum Bilirubin is too high .Then Doctor advice USG abdomen ,to find out cause of obstruction in Bile duct
There is another Type of Jaundice ,where Anorexia is not severe .But there is history of Blood Transfusion or STD ( Sexual Trasmitted Disease) .In this case Doctor will suspect Jaundice due to Hepatitis B virus .This is also called as Serum Jaundice .Diagnosis is confirmed by doing Blood Tests as Australia Antigen or HBsAg .This Test becomes Positive
Here we must understand that ,even if you are taking Ayurvedic or Homeopathic or Naturopathy Treatment ,above said Investigations are must to get done !